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Pharmaceutical preparations and substances in the nature of hormone replacement therapy [HRT]; pharmaceutical preparations and substances for use in relation to endometrial hyperplasia; pharmaceutical preparations and substances for use in relation to the prevention and treatment of endometrial carcinoma; pharmaceutical preparations and substances for use as an adjunct to oestrogen therapy; pharmaceutical preparations and substances for use in relation to the treatment of progesterone deficiency; pharmaceutical preparations and substances for use in relation to assisting conception and supporting gestation; pharmaceutical preparations and substances for use in relation to pregnancy; pharmaceutical preparations and substances for use in relation to prevention of premature birth; pharmaceutical preparations and substances for use in relation to reproductive health; pharmaceutical preparations and substances for use in relation to conception; pharmaceutical preparations and substances for use in relation to fertility; fertility enhancement preparations; pharmaceutical preparations and substances for use in relation to the treatment of infertility; pharmaceutical preparations and substances for use in gynaecology; Pharmaceutical preparations for the treatment of menopause; Pharmaceutical preparations and substances for the alleviation of menopause-related symptoms