5
Pharmaceutical, veterinary and sanitary preparations; preparations for diagnosing viruses and viral infections; products for applied and basic research in the fields of virology, cellular biology, molecular biology, genetic engineering, genetic analysis (in particular analysis of viral genomes), protein structure analysis, in particular analysis of the structure of viral proteins
42
Applied and basic research with the aim of clarifying the interaction of cellular and viral factors, and in particular protein-protein, protein-nucleic acid, and nucleic acid-nucleic acid interaction, with the aim of developing new types of antiviral drugs and therapies; applied and basic research using methods from the fields of proteomics and genomics, and in particular the identification of proteins using mass spectrometry, the examination of protein interaction using plasmon resonance spectrometry (biacore) and affinity binding methods, including protein interaction using microcapillary systems or antigen-antibody interaction for immunoprecipitation, protein separation using multidimensional electrophoresis systems and various chromatography systems (HPLC and FPLC), clarification of gene sequences using DNA and RNA sequencing methods, analysis of protein and nucleic acid sequences using bioinformatics methods and systems, manufacture of viral and cellular proteins using peptide synthesis methods and recombinant DNA technology; applied and basic research in the field of virology, in particular human pathogenic retro, hepatitis, influenza and ebola viruses, including human immunodeficiency (HIV) viruses as pathogens of AIDS, human hepatitis B and C viruses (HBV and HCV) as the main pathogens of chronic liver inflammation, cirrhosis of the liver and liver cell carcinoma, the influenza A virus as pathogen of influenzal infection, the eboal virus as pathogen of haemorrhagic fever; applied and basic research in the field of virology, in particular for analysing the interaction of viral factors and the host cell in the replication cycle, and in processes of virus entrance, the replication of viral genomes, the integration of viral genomes in host genomes, virus assembly, the release of viruses, the interaction of viral factors and uninfected cells; applied and basic research in the field of virology, in particular the molecular structure and functioning of viral proteins, including the virus protein R (Vpr) of HIV-1, HIV-2 and SIV (simian immunodeficiency virus), the virus protein U (Vpu) of HIV-1, the regulatory Tat protein of HIV-1, HIV-2 and SIV (simian immunodeficiency virus), the regulatory Nef protein of HIV-1, HIV-2 and SIV, the regulatory Vif protein of HIV-1, HIV-2 and SIV, the regulatory Rev protein of HIV-1, HIV-2 and SIV, the p6 Gag protein of HIV-1, the regulatory PB-F2 of the influenza A virus, the matrix protein of ebola viruses, the regulatory PBX protein of HBV; applied and basic research in the field of virology, in particular examining the interaction of viral factors and cellular folding enzymes (chaperones), including peptidyl-prolyl-isomerases (PPIases); applied and basic research in the field of virology, in particular examining the interaction of viral factors and cellular proteases, including the ubiquitin-proteasome system; applied and basic research in the field of virology, in particular examining the interaction of viral factors and cellular receptors, including the human T-cell receptor CD4 or chemokine receptors; applied and basic research in the field of virology, in particular in the use of substances which block virus-cell interaction, including proteasome inhibitors (including lactacystin or epoxomicin), PPIase inhibitors (including cyclosporin A), receptor inhibitors (including chemokine), inhibitors of cell-virus membrane fusion, inhibitors of assembly domains in retrovirus Gag proteins; applied and basic research in the field of virology, in particular for manufacturing diagnostics (diagnostic preparations) for the qualitative and quantitive assessment of viral factors in biological samples with the aim of establishing the infection status; analysis of protein-protein interaction using two-hybrid systems and phage display, analysis of cellular targets with the aid of kinases and phosphatases, and of core domain structures; scientific and industrial research
44
Medical and veterinary care, hygienic and beauty care